Developments in Low-Resolution Biological X-ray Crystallography
News Aug 08, 2011
Despite the recent substantial technological developments in X-ray crystallography, solving and refining structures at low resolutions remain substantial challenges. Many macromolecular crystals, especially those of large molecules or multicomponent assemblies, diffract X-rays to resolutions that are worse than 3.5Å.
The full article, written by Fred Dyda of the National Institute of Diabetes and Digestive and Kidney Diseases, is published online in F1000 Biology Reports and is free to access.