ESA Biosciences, Inc., has produced several application notes demonstrating the use of its Corona® Charged Aerosol Detector with HPLC for chemical analysis.
The notes cover applications involving antibiotics, carbohydrates, carboxilic acids, glycerol, impurity testing, lipids and peptides. The Corona provides response independent of structure, wide dynamic range and low nanogram sensitivity in a detector that is easy to install and use.
“The need for universal HPLC detection in analytical laboratories is widespread,” said John Christensen, ESA Biosciences Vice President.
“While several detection technologies are currently being used, there is significant room for improvement in performance characteristics. To help address the many challenges of universal detection, we have the developed the Corona technology to make life easier and more effective for analytical scientists.”
According to ESA, the Corona CAD’s many benefits include: high sensitivity (low ng limits of detection), consistent response factors not dependent on analyte properties, broad and useful dynamic range (four orders of magnitude: ng - lg quantities), excellent reproducibility, and broad applicability.