ESI-MS: A Technique to Access the Information beyond the Molecular Weight of the Analyte
News Jun 01, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules. There have been extensive studies on the mechanism of formation of charged gaseous species by the ESI. Several groups have investigated the origin and implications of the multiple charge states of proteins observed in the ESI-mass spectra of the proteins. The charged analytes produced by ESI can be fragmented by activating them in the gas-phase, and thus tandem mass spectrometry has been developed, which provides very important insights on the structural properties of the molecule. The review will highlight recent developments and emerging directions in this fascinating area of research.
The review article is published online in the International Journal of Analytical Chemistry and is free to access.
Arsenic Exposure in U.S. Public Drinking Water Declines Following New EPA RegulationsNews
New research found that exposure to arsenic in drinking water was significantly reduced among Americans using public water systems following the Environmental Protection Agency regulation on maximum levels of arsenic. However, there were no improvements in arsenic exposure rates among users of private wells, which are not federally regulated.READ MORE