Grace Announces Additional Patent Notices of Allowance for Flash Chromatography Technology

W. R. Grace & Co. has announced that the U.S. Patent and Trademark Office has granted three additional Notices of Allowance related to the company’s Reveleris® flash chromatography system.

The benefits derived from these allowed claims enable streamlined purification of new chemical/biological entities for drug discovery.

These notices describe actively controlling the split flow, using chromaphoric solvents, and collecting fractions based on a wavelength range during flash chromatography.

These techniques streamline purification of new chemical/biological entities during drug discovery by increasing recovery, improving reliability and simplifying instrument operation.

Grace previously announced receipt of a patent for the use of Evaporative Light Scattering Detection (ELSD) with flash chromatography, a key part of the Reveleris® flash chromatography system.

“These additional U.S. Patent Allowances further confirm our leadership in flash chromatography technology,” said Laurie Andriate, Vice-President/General Manager of Discovery Sciences, a product line of Grace Materials Technologies.

Andriate continued, “Our cutting-edge technology has advanced the capabilities of flash chromatography, resulting in cost savings and productivity enhancements for our customers.”

The award winning Reveleris® flash chromatography system and Grace’s innovative silica cartridges are used by most leading pharmaceutical companies in the world.

Grace has combined its expertise as the world’s largest manufacturer of specialty silica gel with its pioneering ELSD know-how to optimize flash purification for a broad range of applications.