We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Neutrons Observe Vitamin B6-dependent Enzyme Activity Useful for Drug Development

News   Oct 19, 2017 | Original Story from Oak Ridge National Laboratory

 
Neutrons Observe Vitamin B6-dependent Enzyme Activity Useful for Drug Development

An ORNL-led team used neutrons to observe the AAT enzyme, a vitamin B6-dependent protein, and found that the chemical reaction occurred only in one active site. Nuclear scattering length density maps (colored mesh) highlight the positions of critical hydrogen atoms, including a low-barrier hydrogen bond (magenta mesh) not thought to exist in AAT, which may be crucial for catalysis. Credit: Jill Hemman and Andrey Kovalevsky /Oak Ridge National Laboratory, US Dept. of Energy.

 
 
 

RELATED ARTICLES

Regular Use of Prescription Meds for Pain and Sleep Increases Frailty Risk by 95%

News

Researchers have demonstrated statistically significant associations between self-reported regular use of prescription drugs for pain and/or sleep, and longitudinal risk of frailty in adults 65 years and over.

READ MORE

Mathematical Method Provides Deeper Understanding of Drug Interactions

News

Researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences have developed a new methodology characterizing more precisely how drugs influence each other when combined during treatment.

READ MORE

Could Anthrax Help Fight Bladder Cancer?

News

A team from Purdue University has come up with a way to combine the anthrax toxin with a growth factor to kill bladder cancer cells and tumors.

READ MORE

 

Like what you just read? You can find similar content on the communities below.

Drug Discovery

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE