Post Purification Sample Handling
News Feb 23, 2016
Genevac has developed a suite of proprietary technological solutions to facilitate post purification sample handling, including reformatting. For labs undertaking purification using Normal Phase HPLC, SFC or Flash chromatography – removal of organic solvents can be simply, productively and safely carried out in a Genevac centrifugal evaporator (EZ-2, ROCKET, Rocket Synergy or HT Series III).
Where the nature of the sample being concentrated can lead to solvent bumping (e.g. natural products) - Genevac's DriPure® technology is proven to completely eliminate this troublesome and time-consuming problem.
The evaporation of aqueous acetonitrile (or methanol / ethanol) fractions resulting from
Reverse Phase HPLC is a widely carried out application on many Genevac evaporator systems. A multiple stage method has been developed for the EZ-2 evaporator to remove the organic solvent without freezing the water, remove the water, and then dry any remaining stubborn solvent.
Alternatively, the unique LyoSpeed™ fast lyophilisation method can be used in Genevac HT series evaporators to produce dry (solvent-free) powders from samples that previously could only be produced as gums and oils. Recent advances in condenser technology, in particular the high power -75°C cold trap, available on HT Series III and Rocket Synergy evaporators, has led to significant advances in lyophilisation success rates.
During post purification handling - samples typically need to be reformatted from fraction tubes or flasks, into a small vial for compound storage. For this specific time consuming task, Genevac developed SampleGenie™ technology. SampleGenie™ enables a large volume to be dried (or lyophilised) directly into a small storage vial in a fraction of the time taken by traditional evaporation methods that require you to reformat samples from a flask or multiple tubes into a vial.
Rapid Removal of Arsenic From Drinking Water...By Moss!News
A moss capable of removing arsenic from contaminated water has been discovered by researchers. And it happens quickly – in just one hour, the arsenic level is so low that the water is no longer harmful for people to drink.READ MORE
Stable Beta-Amyloid Dimers Identified in Alzheimer’s BrainsNews
A recent study exploited state-of-the-art mass spectrometry to provide the first direct evidence of beta-amyloid dimers in patients with Alzheimer’s disease and points to the potential of these molecules as biomarkers. Beta-amyloid dimers may be the smallest pathological species that trigger Alzheimer’s disease.
A Fatal AttractionNews
Malaria causes the bodies of its human hosts to emit specific odours from the skin that make the hosts even more attractive to mosquitoes, perpetuating transmission. Researchers have now identified the odours as organic hydrocarbons heptanal, octanal and nonanal, whose discovery could bring relief to a disease that claimed nearly half a million lives in 2016.READ MORE