Proteros Biostructures Achieve Milestone in Fragment-Based Protein Crystallography Collaboration
News Jun 21, 2007
Proteros biostructures GmbH has announced that the first milestone of their research collaboration with Bayer HealthCare in the field of fragment-based protein crystallography has been successfully achieved, triggering the associate milestone payment.
In the collaboration, which started in June 2006, Proteros applies its target know-how, industrial process and proprietary Free Mounting System (FMS™) and Picodropper™ technologies to deliver protein-ligand-structures of active fragments from Bayer HealthCare’s drug discovery programs to Bayer HealthCare. Under the terms of the agreement Proteros will also receive a copy of the jointly selected fragment library for its own use.
”We are pleased to proof that Proteros’ experience, has allowed delivery of valuable protein-fragment-structures to Bayer HealthCare within the envisioned time frame”, stated Torsten Neuefeind, Ph.D., Chief Executive Officer of Proteros.
Researchers have solved the structures of the cancer-promoting enzymes USP25 and USP28, and identified significant differences in their activities. This knowledge provides the molecular basis for the development of new and highly specific anti-cancer drugs, with a low risk of side-effects.READ MORE