Spark Holland Enters into new Partnership with DiLab for Automated Blood Sampling in Pharmacokinetic Studies
News Aug 14, 2009
The AccuSampler Micro permits automated serial withdrawal of blood samples as small as 5µl up to 50µl from small lab animals, such as mice, for pharmacokinetic studies. Adaptation of the AccuSampler will enable users to place Symbiosis trays with blood collection cartridges in the AccuSampler. Trays with collected blood samples can then be placed directly in the Symbiosis system for online SPE-LC-MS analysis, without any further manual sample work-up. The combination of collecting accurately measured small blood volumes and direct processing for online SPE-LC-MS allows serial blood sampling from small lab animals such as rats and mice, for an entire pharmacokinetic study with a single animal. Not only will this significantly reduce the number of lab animals, but it also results in better pharmacokinetic data. In addition, throughput of pharmacokinetic studies is enhanced while providing more safety and less operator errors.
The DiLab ABS AccuSampler Micro is compliant with the “3R” guidelines for animal welfare as issued by the National Center for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) in London.
New Partnership to Provide Bioanalytical and DMPK ServicesNews
Concept Life Sciences, the integrated drug discovery, development and analytical services company, and Alderley Analytical, bioanalytical Contract Research Organisation (CRO), today announced they have signed a partnership agreement to provide high-value bioanalytical and DMPK study services.