The Design of Macromolecular Crystallography Diffraction Experiments

Abstract
The measurement of X-ray diffraction data from macromolecular crystals for the purpose of structure determination is the convergence of two processes: the preparation of diffraction-quality crystal samples on the one hand and the construction and optimization of an X-ray beamline and end station on the other. Like sample preparation, a macromolecular crystallography beamline is geared to obtaining the best possible diffraction measurements from crystals provided by the synchrotron user.

The article is published online in Acta Crystallographica Section D, Biological Crystallography and is free to access.