Thermo, Evans Analytical Group Form Joint Effort to Expand GDMS Applications
News May 15, 2014
Scientists analyzing non-conductive, high-purity materials will soon be able to apply powerful high-resolution glow discharge mass spectrometry (GDMS) to this task. This will open the technique, for example, to analysis of high-purity sapphire used for flat panel displays, ceramics, alumina powder and other desirable applications, including thin-layer depth profiling of hard drive components.
GDMS is currently used for analyzing conductive materials such as high-purity metals and semiconductors used in microelectronics, renewable energy, aerospace, medical devices and nuclear power.
To extend the method’s capability to non-conductive materials, Thermo Fisher Scientific has collaborated with leading materials characterization lab Evans Analytical Group (EAG) to add “pulsed” ion source technology to GDMS. The goal is to make a pulsed-mode ion source an integrated feature of a commercial GDMS platform.
Standard glow discharge MS for elemental analysis uses the sample as a cathode, and electrical current is applied to it to form a glow between sample and an anode. Using pulsed-mode, the surface of the sample is “sputtered” by impacting gas ions, and the sputtered atoms are measured by a mass analyzer. This highly-sensitive technique requires little or no sample preparation and generally delivers high-quality results in about 10 minutes. In addition to accommodating non-conductive samples, pulsed-mode ionization also enhances instrument stability, data precision, and lower-energy sputtering produces better results with some types of samples.
“I strongly believe that the fast flow source in pulsed mode is the best glow discharge source for analytical mass spectrometry,” said Karol Putyera, vice president of EAG.
“We’re very excited at the prospect of making the benefits of glow discharge mass spectrometry available to the wider materials science community,” said Joachim Hinrichs, applications specialist for glow discharge and inductively-coupled plasma mass spectrometry for Thermo Fisher Scientific.
Arrow Poison Potential Male Birth ControlNews
Women have many options for oral contraceptives that are safe, effective and reversible, but despite decades of research, men have none. Now, scientists report a rat study that shows they finally have a good lead for a male birth control pill. It's based on ouabain, a plant extract that African warriors and hunters traditionally used as a heart-stopping poison on their arrows.READ MORE
Robust Multiplex Mass Spectrometric Assay for Screening Small-Molecule InhibitorsNews
A new original research article presents a fast, sensitive, and robust methodology for screening small molecule inhibitors against CD73/Ecto-5'-Nucleotidase, a promising target for developing anti-cancer drugs.READ MORE