2D FT-ICR MS/MS Analysis of lgG1
Recombinant monoclonal antibodies and derivatives are widely used as therapeutic drugs. Post-translational modifications during the manufacturing process and storage can result in product-related impurities. PTMs can change the efficacy, toxicity, or the clearance of the antibody; therefore they need to be well monitored.
Download this poster to learn how you can achieve 2D FT-ICR MS/MS analysis of IgG1 that includes:
- Effective analysis of bottom-up mixtures.
- Selectively analyzes phosphopeptides.
- A new approach to top-down proteomics.
- An alternative to MS/MS.