Latest Posters

Analyses of the M. truncatula extracts were performed, and data processing focused on qualitative analyses. This provided the opportunity for known analyte verification and unknown identification in a meaningful matrix and the demonstration of the key attributes and benefits of GC-HRT.

High resolution GC-TOFMS on the Pegasus GC-HRT allowed for quick and easy non-targeted screening of extractables from a common consumer product: the ubiquitous cell phone case. Most components could be identified with high similarity scores against commercial libraries. However, even when faced with low similarity scores against commercial libraries, such as in the case of Biphenol AF, the ability to rely on high mass accuracy allowed for confident identification of components.

-Source temperature was commonly the most significant variable for maximizing molecular ion peak area.
-Chromatographic peak shape was temperature dependant primarily for the non-volatile compounds.
-Ionization conditions were optimized to maximize molecular ion for a variety of compound classes.
-Ionization conditions do change the peak shape and peak area, which relates directly to library searchability.

GC-HRT methods utilizing hydrogen carrier gas were developed for analysis of representative specialty chemical, forensic, and metabolomic markets.

• To demonstrate a fully automated workflow for both liquid injection and headspace for GC and GC/MS.
• Automatically optimize analysis conditions and derivatization parameters.
• Automate standard preparation and derivatization procedures.
• Reduce analysts time involved in the analysis.
• Compare manual versus automated preparation of standards.

• Automated Bligh and Dyer extraction for metabolomic studies.
• Dual-column UHPLC setup for the analysis of the polar and lipidic fractions.
• Alternating acidic and basic mobile phase for the separation of the polar fraction.
• Identification of unknown compounds by SWATH HR MS2 spectra acquisition.

The PAL RTC provides an affordable and reliable platform optimised for medium-throughput peptide preparation for shotgun-proteomics based mass spectrometry.
Reduce hands-on time on repetitive work!
Increase consistency!
Increase reproducibility

This poster has demonstrated GC-TOFMS instrumentation applied to characterize beer-related samples. The ability to isolate and identify individual analytes through chromatographic resolution, mathematical deconvolution, and mass spectral searching to library standards provides good insight to various stages of production.

Comprehensive study of regulation in myxobacteria with an untargeted metabolomics setup using Isotopic Ratio Outlier Analysis (IROA) and UHR-Q-TOF

Reliable relative quantitation of known and unknown metabolites from a myxobacterial mutant strain in response to induction of the transcriptional antirepressor taA

Compound identification facilitated by the use of ultra-high resolution MS and the knowledge of the number of carbons in each molecule due to IROA

Children’s consumer products have been an active focus for study and regulation due to their ability to expose infants and children to potentially damaging and dangerous chemicals.