Latest Posters
Poster
Novel Role of the Innate Immune DNA Sensor IFI16 (Interferon Gamma Inducible Protein 16) as a Major Epigenetic Modulator During KSHV Infection and Lytic Reactivation
Studies have shown that IFI16 acts as an antiviral restriction factor against a number of DNA viruses, by inhibiting viral replication or transcription through epigenetic modifications. However, till date, no specific epigenetic function of IFI16 has been identified. Here, we have discovered that IFI16 recruits two histone methyltransferases on the KSHV episome leading to altered Histone H3K9 methylation, thus regulating its lifecycle.
Poster
Lymphatic Wall Remodeling with Systemic and Tissue-Associated Inflammation in Obese Zucker Rats
Obesity Leads to Lymphatic Wall Remodeling and Systemic and Tissue-Associated Inflammation in Zucker Rats
Poster
Environmental Exposures and Inflammatory Bowel Disease in Childhood
Inflammatory bowel diseases (IBD) often present in adolescence and affect >1.4 million persons in the US. Environmental exposures, notably air pollution and weather, have been suggested to contribute to IBD disease activity. Our goal was to evaluate relationships between environmental exposures and the prevalence and disease activity of pediatric IBD using novel data sources that take into account geographic location.
Poster
Correlations among the Toddler Gut Microbiome and Health Status Variables
Establishment and succession of the human microbiome begins at birth and microbial composition adapts alongside human development and growth. Development of a healthy signature microbial community has significant effects on health.This study followed 18 very low birth weight (VLBW) infants, measured initially in the from Neonatal Intensive Care Unit (NICU), at the age of two to three years old.
Poster
C1 Complement mediates human cord blood serum derived APP α-secretase cleavage activity in vitro
Our results indicate that CBS contains proteins that promote α-secretase like enzymatic activity. LC-MS/MS analysis in CBSF and AgBSF revealed the presence of 142 proteins of which C1 subunits and alpha-2-macroglobulin showed significantly greater levels in αCBSF compared with αAgBSF. further study showed,C1 subunits can enhance sAPPα production and Aβ reduction in cell culture condition
Poster
Alterations in Immunophenotype of Autoimmune-prone Hypomorphic RAG-deficient Patients with CID-G/AI Phenotype
Patients with partial deficiency of recombination-activating genes 1 or 2 (RAG1/2) can present with a wide spectrum of primary immunodeficiencies including combined immunodeficiency with granuloma and/or autoimmunity (CID-G/AI). Prior case reports have highlighted alterations in B and T cell compartments; however comprehensive characterization of these cell populations with focus on autoreactive-prone subsets has not been reported.
Poster
Fingerprinting the Terpene Profiles of Various Cannabis Strains using GC and GCxGC with High Performance TOFMS
The Pegasus BT 4D facilitates fast and confident cannabis product “fingerprinting” through enhanced two-dimensional chromatographic resolution and high performance TOFMS.
Robust compound identification was achieved through spectral similarity searches of large, well-established databases, mass D determinations, and retention index filtering.
Robust compound identification was achieved through spectral similarity searches of large, well-established databases, mass D determinations, and retention index filtering.
Poster
Using Remote Sensing Methodologies to Combat Schistosomiasis in Northern Senegal
Schistosomiasis is associated with poverty, a lack of clean water and sanitation and is is transmitted through snail vector. Remote sensing methodologies were used to identify types of vegetation that are significantly associated with snail presence as previous studies had shown that removal of certain aquatic vegetation decreased the prevalence of schistosomiasis in nearby villages.
Poster
High Speed Analysis: Combining Fast GC with Time-of-Flight Mass Spectrometry for Complex Sample Analysis in Under One Minute
The demand for more efficiency and productivity in the laboratory has led to applications using Fast GC-MS methods for routine analysis in a wide range of fields.
Poster
Screening of ALDH2 Interactome by Combined Immunoprecipitation and Mass Spectrometry
ALDH2 may have an unidentified protein interaction network, which would help elucidate its importance in various cellular functions. The combination of immunoprecipitation and mass spectrometry will give us insights that could not be easily attained otherwise.
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