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Applications of Mass Spectrometry Targeted Assays for Quantitative Analysis of Cancer Signaling Proteins

The AKT/mTOR pathway and the proteins involved play a central role in tumor progression and drug resistance. Quantitative measurement of alterations in the expression of pathway proteins and post-translational modifications (PTMs) is necessary for understanding cancer biology. However, highly accurate monitoring of these pathway proteins has not been achieved.

Download this poster to discover more about the analysis of pathway proteins, including:

  • Why their analysis has been inaccurate.
  • How to achieve accuracy using mass spectrometry.
  • How multiple pathway proteins can be quantified simultaneously.