Development of an Analytical Strategy for Simultaneous Determination of Multiple Contaminants in Paper Food Packaging
Poster Nov 05, 2014
Adam Vavrouš (1), Lukáš Vápenka (2), Kristina Kejlová (1), Jitka Sosnovcová (1), Dagmar Jírová (1)
Food packaging materials were reported as a potential source of various xenobiotics. In this study a multi-analyte method for simultaneous determination of particular compound groups, namely polycyclic aromatic hydrocarbons, ink photoinitiators, polyfluorinated compounds, phthalate and bisphenol-type endocrine disruptors (70 analytes in total) in food-contact paper was developed and validated. Sample preparation steps were optimized resulting in a high throughput process, which consists of an ultrasonic-assisted solvent extraction and QuECheRS-based liquid-liquid partition. Analysis by means of gas and high performance liquid chromatography coupled to tandem mass spectrometry provided limits of quantification ranging from 0.0025 to 0.21 mg/kg. At spiking levels of 0.025 and 0.25 mg/kg recovery was above 92% and a requirement for precision (HORRAT<1.67) was met by 69 analytes. Supported by IGA MZ ČR NT 14375-3/2013.
Proteomics and Substrate Based MS Imaging of Xenobiotic Metabolising Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent ModelPoster
Untargeted proteomics analysis showed that human skin and a commercially available living skin equivalent model exhibit a similar distribution of xenobiotic metabolising enzymes. A new technique, substrate based mass spectrometry imaging (SB-MSI) was developed during this study.READ MORE
Development and Assessment of Non-Infected and Infected Skin Models Using MALDI-MSIPoster
Infections have detrimental effects on wound healing leading to chronic wound formation. The use of labskin,a living skin model, in combination with mass spectrometry imaging, provides a good model for assessing wound healing factors.READ MORE
Overcoming the Challenges of Analysing Ionic Polar Pesticides in FoodPoster
Here, the novel application of the Waters’ Torus DEA column is presented, showing the improved performance of a UPLC-MS/MS method for the underivatised
analysis of glyphosate and a selection of other anionic pesticides.