Development of an Analytical Strategy for Simultaneous Determination of Multiple Contaminants in Paper Food Packaging
Poster Nov 05, 2014
Adam Vavrouš (1), Lukáš Vápenka (2), Kristina Kejlová (1), Jitka Sosnovcová (1), Dagmar Jírová (1)
Food packaging materials were reported as a potential source of various xenobiotics. In this study a multi-analyte method for simultaneous determination of particular compound groups, namely polycyclic aromatic hydrocarbons, ink photoinitiators, polyfluorinated compounds, phthalate and bisphenol-type endocrine disruptors (70 analytes in total) in food-contact paper was developed and validated. Sample preparation steps were optimized resulting in a high throughput process, which consists of an ultrasonic-assisted solvent extraction and QuECheRS-based liquid-liquid partition. Analysis by means of gas and high performance liquid chromatography coupled to tandem mass spectrometry provided limits of quantification ranging from 0.0025 to 0.21 mg/kg. At spiking levels of 0.025 and 0.25 mg/kg recovery was above 92% and a requirement for precision (HORRAT<1.67) was met by 69 analytes. Supported by IGA MZ ČR NT 14375-3/2013.