PASEF Enhances the Speed, Sensitivity and Selectivity of Label-free Quantification
Poster Apr 05, 2019
The Parallel Accumulation Serial Fragmentation (PASEF) method enables faster acquisition of fragment ion spectra from isolated precursor ions, improving sensitivity without sacrificing spectral quality.
However, the volume of data that is generated and the addition of an extra separation dimension can constitute a challenge for the software.
Download this poster to learn how an adapted version of PEAKS™:
- Enables identifications and label-free quantification from PASEF runs
- Enhances the speed, sensitivity and selectivity of label-free quantification
The changing landscape for antibody-derived therapeutics, such as bi-specific monoclonal antibodies, Fab fragments and Fc-fusion proteins brings new purification challenges in the downstream processing of these molecules. Standard chromatography resins, such as Protein A, may not result in the most efficient purification process.READ MORE