Quantitative, Comprehensive Multi-pathway Signaling Analysis
Poster Oct 21, 2019
Bhavin Patel; Penny Jensen; Aaron S. Gajadhar; Sebastien Gallien; Jae Choi; Romain Huguet; Graeme McAlister; Derek Bailey; Shannon Eliuk; Markus Kellmann; Tabiwang N. Arrey; Alexander Harder; Andreas Huhmer; Kay Opperman; John C Rogers
Post-translational modifications (PTMs), such as phosphorylation, are crucial in controlling key aspects of protein function, including interactions in signaling pathways. Identification and quantitation of the phosphorylation state of proteins involved in cell progression, metabolism, growth, and disease is critical for the continued elucidation of cellular function.
Despite improvements in new mass spectrometry instrumentation, phosphoproteomic analyses still face challenges.
Download this poster to discover more about the analysis of pathway proteins, including:
- Why their analysis has been inaccurate.
- How to achieve accuracy using mass spectrometry.
- How multiple pathway proteins can be quantified simultaneously.