Stable N-phosphorylated triazol-5-ylidenes
Poster Nov 12, 2012
Kirilchuk,A. A.; Marchenko,A. P.; Koidan, H. G.; Zarudnitskii, E. V.; Huryeva, A. N.; Yurchenko, A. A.; Kostyuk, A. N.
Continuing our study on mechanism of phosphorylation of nitrogen–containing heterocycles we report on our results of phosphorylation of trizoles and synthesis of new type of chelating ligands bearing two coordination sites – carbene and trivalent phosphorus.
Getting Ready For The 21st Century Photochemistry - Teaming Up Continuous Flow And LEDPoster
Corning has developed a scalable photo flow reactor with an optimized LED lighting(3). The presented experimental data will demonstrate the various benefits of performing photo chemistry in a continuous way, especially the simplicity of scaling up and enormous energy savings, which are today the main stopper for industrial application.READ MORE
The Pathogen Box: A Catalyst for Neglected Disease Drug DiscoveryPoster
Modelled after the Malaria Box, the Pathogen Box contains ~400 diverse drug-like molecules active against neglected diseases of interest such as Chagas disease, cryptosporidiosis, hookworm, sleeping sickness, leishmaniasis, lymphatic filariasis, malaria, onchocerciasis, schistosomiasis, trichuriasis, tuberculosis.READ MORE
Selective Debenzylation of N-Benzyloxypyrazinones in FlowPoster
Selective and reproducible debenzylation of benzyloxypyrazinones by using catalytic transfer hydrogenation in flow chemistry to yield N-hydroxypyrazinones. The flow methodology enabled us to avoid overreduction of the compounds to pyrazin-2(1H)-ones.READ MORE