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Agilent Announces Intelligent System Emulation Technology

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Agilent Technologies Inc. has announced the introduction of the revolutionary Intelligent System Emulation Technology. ISET harnesses the wide power range and superior accuracy and performance of the Agilent 1290 Infinity LC to emulate other systems for seamless transfer of methods between LCs, regardless of brand.

This capability makes the 1290 Infinity LC the world’s first truly universal LC system, as it can execute other high-performance and ultra high-performance methods and deliver the same chromatographic results without any change of the instrument or the original method.

The 1290 Infinity LC together with ISET allows researchers to do the following:

• Emulate other UHPLC and HPLC instruments by a simple mouse click.
• Run existing UHPLC and HPLC methods without modifying method or system.
• Deliver the same retention times and peak resolution for better method transfer.

ISET accelerates and facilitates inter-laboratory LC method transfer. QA/QC labs can now make a safe investment for the future, since they can continue to run their legacy methods while taking full advantage of the UHPLC speed, resolution and sensitivity of the 1290 Infinity LC. Labs are now able to speed up their method development with UHPLC performance and fine-tune the new method by emulating the target system, confident that the method will run as intended.

“Instrument-to-instrument method transfer is often problematic, especially in highly regulated industries, because any modifications of the instrument and original method should be avoided,” said Christian Gotenfels, 1290 Infinity LC product manager for Agilent. “Agilent was the first company providing seamless method transfer between the 1100 Series, 1200 Series and the new 1220/1260 Infinity LC.”

“This is the beginning of a new era,” said Stefan Schuette, senior marketing director of Agilent’s Liquid Phase Analysis Division. “Development laboratories, QA/QC departments, and contract research and manufacturing organizations now will be free to develop, validate and execute all methods on a single instrument.”

The 1290 Infinity LC with ISET will be available in the third quarter of 2011. Existing 1290 Infinity LC systems are fully compatible with and upgradeable to ISET.