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Agilent Technologies Introduces Improvements to Single Quadrupole Mass Spectrometers
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Agilent Technologies Inc. has introduced enhancements to its 6100 Series of single quadrupole mass spectrometers that provide customers with a wide range of benefits.
The specific benefits are: for high-throughput labs, the ability to obtain high-quality mass spectrometer (MS) data across very narrow chromatographic peaks (in the range of one second in peak width); maximum spectral information confirming that the correct peaks are being identified; fast POS/NEG mode switching, providing more information, even for the very narrow chromatographic peaks; and more universal detection of chemical entities where it is difficult to predict the best ionization conditions.
In addition to the ultra-fast positive/negative switching, the research-grade model Agilent 6140 now features fast scanning at 10,000 amu/sec with data quality.
All four of the Agilent 6100 single quad models have improved injection-to-injection cycle time, providing further efficiencies for high-throughput labs. Combined with additional capabilities, including the multimode source’s ability to perform simultaneous electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI), these upgraded systems enable nearly 100-percent coverage for almost all drug candidates.
Agilent 6100 Series Quadrupole LC/MS systems put the sensitivity, selectivity, and information content of mass spectrometry into a compact package. Four models are available:
• The Agilent 6140 Single Quad is a high-performance, fast-scanning model designed for high-throughput laboratories. With a scanning speed of 10,000 amu/second, it keeps pace with the Agilent 1200 Rapid Resolution LC system.
• The Agilent 6130 Single Quad is a full-featured research-grade model, offering 1-picogram sensitivity, multi-signal capability and a full mass range to 3,000 amu.
• The Agilent 6120 Single Quad offers 10-picogram sensitivity and positive/negative switching capability. It enables drug discovery and development researchers to analyze new compound libraries.
• The Agilent 6110 Single Quad is an entry-level model offering 10-picogram sensitivity.
Like all Agilent 6000 Series instruments, the single quads feature Agilent’s autotune function, which improves ease of use, uptime and productivity by eliminating the need for manual recalibration from sample to sample.
