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Bruker Redefines Ion Trap Mass Spectrometry with the Introduction of amaZon™ Ultra-Sensitive Ion Trap

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Bruker Daltonics launches the next-generation ion trap amaZon™ series. Delivering 10x improved MS/MS sensitivity over current platforms, novel technology for accelerated data acquisition, enhanced mass resolution, and second-generation ETD/PTR capabilities, this high performance ion trap delivers data quality and flexibility for a broad variety of applications, the company claims.

According to Bruker Daltonics, the amaZon builds upon its long experience in ion trap technologies, and is designed to enhance capabilities in research areas such as bottom-up proteomics, high-throughput and ultra-sensitive PTM analysis, metabolomics, compound screening and identification, and detailed chemical and structural analysis. The amaZon series is offered in two versions: amaZon ETD for proteomics, and amaZon X for small molecule analysis and applied markets.

The new amaZon incorporates key inventions for unprecedented ion trap capabilities:

• First commercial introduction of a double ion funnel transfer in ion traps, delivering a new benchmark for sensitivity. Unrivalled scan speed of 52,000 u/sec at better than unit resolution for UPLC applications and maximum duty cycle in data-dependent MS/MS and MSn.

• Ultimate ion trap mass resolving power up to 20,000 in full scan mode across the 50-3000 m/z range: in combination with Bruker’s patented peak recognition technology SNAP IITM, the amaZon provides isotopic peak resolution even for highly charged ion species in ETD/PTR fragment spectra for the confident determination of their monoisotopic masses.

• The latest ETD/PTR technology offering the sensitive peptide and protein fragmentation, as well as high-throughput PTM analysis. Building upon the very successful ETD technology commercialized first by Bruker, the combination of bottom-up CID or ETD and top-down ETD/PTR provides new methodologies for detailed protein characterization.

• Zero Delay Alternating™ acquisition for high-speed ion polarity switching. Up to 20 Hz MS data acquisition in both polarities is ideal in combination with UHPLC separations. Supported by spectral MSn libraries, the amaZon is the ultimate ion trap mass spectrometer for MS/MS based multi-compound screening.