Fast and Specific HSA and IgG Depletion; Vivascience AG Introduces Vivapure Anti-HSA/IgG Kit
Product News Apr 07, 2005
Vivascience has further expanded the Vivapure sample preparation product line by introducing a new human albumin and IgG depletion kit.
The Vivapure Anti-HSA/IgG it utilizes a combination of a Anti-HSA antibody fragment and Protein G resin for specifically depleting albumin and IgG from human samples.
The kit provides (more than)95 % removal of albumin and IgG from 20 ul of human serum along with low non-specific binding of potential serum biomarkers. Albumin and IgG depleted samples are recovered in a low salt buffer, facilitating downstream applications.
With this kit, Vivascience expands its range of Vivapure sample preparation products: Vivapure Anti-HSA Kit for Albumin Depletion, Vivapure Anti-HSA Resin for Albumin Depletion from serum volumes up to 400 ul, and Vivapure Ion Exchange spin columns for sample fractionation.
Vivascience claim that The Vivapure Kit further improves the resolution and detection of lower abundance sample proteins by electrophoresis, chromatography, and mass spectrometry by removing up to 75% of high abundant serum proteins.
The Anti-HSA ligand also shows reactivity against rat and mouse albumin. As Protein G is also efficient at binding rat and mouse IgG, this kit can be utilized for processing samples from the three most frequently encountered sample sources in biomarker research.