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GE Healthcare Launches Capto™ L Chromatography Medium
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GE Healthcare’s Capto L affinity chromatography medium (resin) is designed for the purification of antibody fragments.
It combines a rigid, high-flow agarose matrix with the immunoglobulin-binding recombinant protein L ligand, which has strong affinity for the variable region of antibody’s kappa light chain.
Capto L is therefore suitable for purification of a range of antibody fragments such as Fabs, single-chain variable fragments and domain antibodies.
With its high dynamic binding capacity and high selectivity, Capto L increases process economy and process design flexibility.
Capto L is a BioProcess™ medium supported for commercial manufacturing and enables a high-productivity platform approach to antibody fragment purification.
Availability of flexible formats such as PreDictor™ plates and PreDictor RoboColumn™ units speeds up the screening and optimization of binding and elution conditions.
HiTrap™ and HiScreen™ prepacked columns can be utilized for confirming screening and optimization results in packed bed conditions, as well as for convenient small scale purification.
