Heating Block System Helps Improve Stability Studies

Asynt has supplied a leading European Contract Research Organization (CRO) with a custom heating block system to assist chemists analyzing the thermal stability of multiple samples being prepared for its commercial compound libraries.

Traditionally the CRO had used an offline heating source to heat samples coming from its UPLC system - the process was highly labour intensive, involving manual transfer of samples to and from the UPLC autosampler.

In conjunction with chemists at Asynt, a new, efficient method was developed using a custom designed heating block with locators and format to fit the UPLC autosampler as well as an offline heating tray compatible with a hotplate stirrer.

The new system has been demonstrated to provide more uniform heating to all UPLC samples, eliminate sample mix-ups and significant reduce the labour intensity of the whole process.

The CRO reports that the Asynt custom UPLC heating block system not only has improved their productivity but also is producing more accurate, repeatable thermal stability measurements.