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IDEX Health & Science Launches Film Degasser for Enhanced HPLC Performance


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IDEX Health & Science, LLC (IH&S) has unveiled its new Flat Film Membrane Degasser. In a transition from traditional lumen designs, this technology aims to provide performance control with increased solvent compatibility, performance and efficiency in a smaller footprint device and the control methodology shifts the emphasis from ‘constant vacuum’ to ‘constant performance’, by allowing users to select an optimal degassing efficiency for any HPLC methods.

With an efficient membrane and flow channel design, the Flat Film Degasser aims to deliver low fluidic resistance. The membrane provides sufficient surface area to degas solvents to the highest degree necessary for analytical scale (up to 10 mL/min flow rate) HPLC systems. Combined with flow channel design and shorter fluid and membrane diffusion paths, the rate of degassing is enhanced over tubular/lumen designs, enabling an overall smaller instrument footprint. The system uses a non-metallic flow path, which enables universal application of a single type of degasser to multiple types of HPLC methods.

The new patent pending vacuum control algorithm provides the user experience to integrate degasser into the separation method control protocol and select a given efficiency for any HPLC system. Pressure can be dialed up or down depending on the specifications of the application. This method of adjustment achieves an appropriate level of degassing for any HPLC system design and separation method and enables consistent operation to reduce pervaporation and associated mobile phase concentration changes. The flow restriction aims to be constant, regardless of the applied vacuum.


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