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JPK Announces Release of the NanoWizard® 4 BioScience AFM

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Working closely with their user base worldwide, JPK is pleased to announce their fourth generation AFM product, the NanoWizard® 4 BioScience AFM system. The pioneering manufacturers of nano solutions for life scientists have raised the bar in terms of technical performance to deliver a new applications-driven solution for users. It features fast scanning up to 70 Hertz line rate. Translated, this means users can follow dynamic processes with outstanding resolution through an extremely flexible design. 


JPK have long been leaders in the combination of fully integrated AFM and light microscopy in liquids. The new system is especially designed for integration with advanced optical methods (FLIM, FCS, FRET, confocal, Raman, etc.) as well as Superresolution optics such as SIM, STED or PALM/STORM. This has now been fine-tuned to enable straightforward high resolution quantitative imaging through a new nanomechanical design of the core AFM complemented with the widest range of modes and accessories. 

Performing long term experiments on living cells might be considered a challenge. With NanoWizard® 4 having the highest mechanical and thermal stability on an inverted microscope, this has become routine. This is achieved because JPK uses the lowest noise level for all system components such as a closed-loop scanner & deflection detection system. The electronics ensure the highest quality data. This also improves the performance of JPK’s QI™ quantitative imaging mode. This is especially important for users working with single molecules, live cells and tissues. Using linear Z-movement and collecting a full set of quantitative data in every pixel allows the extraction of quantitative data such as elasticity, adhesion, dissipation, chemical forces or molecular binding sites. All of this is achieved under perfect environmental control – biological samples imaged in liquids in their optimum physiological conditions. 

With more users wishing to perform long-running experiments over prolonged periods yet still being "in contact" with them, JPK has added expanded usability and remote experimental control. The new ExperimentControl™ feature enables the user to both set up and control experiments via the Internet using their PC, tablet or smart phone. This delivers real time data helping users to be more productive in their workflow. 

With the life sciences constantly demanding higher performance, the NanoWizard® platform from JPK delivers a unique BioAFM system that has grown to meet these demands. NanoWizard® 4 BioScience AFM is the latest solution and is designed to answer the advanced and complex questions of tomorrow’s research.