We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

New Hydrophobic Interaction Column from Thermo Fisher Scientific

Listen with
Speechify
0:00
Register for free to listen to this article
Thank you. Listen to this article using the player above.

Want to listen to this article for FREE?

Complete the form below to unlock access to ALL audio articles.

Read time: Less than a minute

Many laboratories analyzing monoclonal antibodies (mAb) regularly encounter situations where they need alternative hydrophobic interaction chromatography (HIC) selectivity. Thermo Fisher Scientific has developed new column chemistry that separates many more of these challenging mAbs, antibody-drug conjugates (ADCs) and proteins.
 
The Thermo Scientific MAbPac HIC-10 HPLC column has been demonstrated to provide selectivity that is different from other commercial HIC columns, including separating many native mAbs, fragments, aggregates, oxidation variants, PEGylated mAbs and ADC.
 
The column’s proprietary chemistry is designed to provide the new selectivity in a high-resolution column with excellent biocompatibility and high recovery. The column is compatible with organic solvent and aqueous mobile phase. It is designed for rugged stability and very low carry-over.
 
“MAbs are the most successful and prominent class of biotherapeutics,” said Ilze Birznieks, product line manager, biocolumns, Thermo Fisher Scientific. “HIC is a popular technique for separating these biomolecules, but researchers have been continually asking for alternative selectivity. This new column responds to these customer demands.”