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New Thermo Fisher Selectris Filters Push Cryo-EM Boundaries with Atomic Resolution

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Thermo Fisher Scientific has introduced two breakthrough imaging filters, the Thermo Scientific Selectris Imaging Filter and the Thermo Scientific Selectris X Imaging Filter, taking cryo-electron microscopy (cryo-EM) to a new level, making it possible to view proteins at true atomic resolution.

Combined with a Thermo Scientific Krios or Glacios Cryo-Transmission Electron Microscope (TEM), the Selectris filters aim to allow biologists to accelerate their structural analysis research by viewing protein structures in unprecedented detail and in less time than was previously possible.

“Cryo-EM has already been a game changer, and our Selectris filters solidify this technique as a ‘must have’ for mapping 3D protein structures,” said Trisha Rice, vice president and general manager of life sciences at Thermo Fisher Scientific. “With a more precise understanding of the connections between proteins and disease, researchers can now speed the path to disease understanding and treatment.”

The Selectris X was designed for researchers seeking industry-leading optical performance, while the Selectris is ideal for those who require maximum efficiency and throughput. Both filters offer a combination of stability and contrast, allowing researchers to produce high quality data, generate fast results, and push the boundaries of resolution to improve single particle analysis and cryo-electron tomography results. The stability of the filters also reduces the need for user intervention and tuning, improving experiment productivity.