Next Generation Phospholipid Removal Microplate
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Porvair Sciences have announced Microluteä PLR, a new product for phospholipid removal. The 96-well microplate is designed to provide effective removal (>99%) of phospholipids and proteins with high levels of reproducibility from plasma and serum samples, while maintaining maximum recovery of target analytes.
Phospholipid-based matrix effects are a major source of variability and inaccuracy in bioanalytical mass spectrometry (MS) analysis. Popular sample preparation techniques like protein precipitation, dilute and shoot or liquid-liquid extraction methods do not completely remove phospholipids. Microlute PLR aims to ensure minimal enhancement or suppression of analyte response by eliminating the source of matrix effects.
Microlute PLR is composed of a solid interconnected network of evenly distributed pores that allow biological fluids to flow smoothly and consistently throughout the active media. This feature is intended to overcome common channeling and breakthrough issues by enhancing the flow of samples throughout the filter and consequently, increasing the recovery of analytes with reproducibility.