Protein Forest Launches Digital Proteomechip™ System for MS Sample Preparation and Data Analysis
Product News Jun 23, 2008
Protein Forest, Inc. has announced launched the digital ProteomeChip™ System at the ASMS meeting in Denver, CO on June 1. The ProteomeChip™ technology fractionates proteins or peptides by parallel isoelectric focusing on dPC™ chips for mass spec analysis and western blotting and the Mass Spec Results and Analysis Tool™ (MSRAT™) bioinformatics software allows the researcher to discover the richness of their dPC™ data produced.
"We are very excited about launching our digital ProteomeChip System as it addresses critical limitations of existing fractionation and sample prep technologies available to researchers today, particularly those that utilize mass spectrometry," said Russell Garlick, Protein Forest’s President and Chief Executive Officer.
"dPC™ chips are precision manufactured to have a difference of 0.05 pH units between adjacent gel plugs with guaranteed reproducibility which allows proteomic scientists the ability to fractionate and concentrate their samples using parallel isoelectric focusing. This technology enables the separation and identification of proteins or peptides often not found by other techniques,” Garlick added.
The dPC™ technology can integrate into existing mass spectrometry workflows. Simply reduce, alkylate and desalt samples before adding to the dPC™ running buffer. Separate for 30 minutes on the dPC™ Chip and protein samples are ready for in-gel tryptic digestion followed by mass spec identification.
The dPC™ technology is compatible with a wide variety of mass spectrometry instrumentation. Alternatively, proteins can be identified by immunoblotting. The combination of the simple workflow and precise dPC™ manufacturing process insures reproducibility from chip to chip and experiment to experiment.