Proxeon Launches EASY-nLC II for LC-MS
Product News Feb 09, 2010
Proxeon has announced the release of the company's second generation instrument, EASY-nLC™ II, optimized for LC-MS applications in proteomics and providing scientists with the opportunity to improve system productivity as a result of a new autosampler and upgraded software.
The company's EASY-nLC platform utilizes a so-called 'split-free' configuration to enhance sensitivity, reproducibility and system stability. The success of this approach has been demonstrated by the original EASY-nLC system which is already established as the system of choice for major mass spectrometry suppliers and proteomics laboratories.
The EASY-nLC II system continues to offer the performance of its predecessor, but has been optimized to increase system productivity. According to Proxeon, the new autosampler features a fully insulated, refrigerated compartment with increased capacity for sample vials and wash-solvents.
A novel 'intelligent flow control' feature enables runs to be preprogrammed to user-defined pressure limits, speeding up equilibration and sample loading steps and eliminating the interruptions that can occur due to pressure fluctuations.
In addition, the automated self-diagnostic tests of the EASY-nLC systems have been enhanced to ensure that users spend even less time troubleshooting.
EASY-nLC II systems are delivered pre-configured to interface and synchronize with any MS system and can be installed and running within hours. Wizard-style programming assists with defining optimal running conditions.
The system is switched between 1- or 2-column configurations and, by using the autosampler as a third pump, can also be used to run two-dimensional mass spectrometry analyzes (2D LC-MS), a configuration shown to enable identification of more proteins than conventional approaches.