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Routine Screening Method Separates Target Antibiotics in DDGS within 15 Minutes
Product News

Routine Screening Method Separates Target Antibiotics in DDGS within 15 Minutes

Routine Screening Method Separates Target Antibiotics in DDGS within 15 Minutes
Product News

Routine Screening Method Separates Target Antibiotics in DDGS within 15 Minutes


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Thermo Fisher Scientific has developed a simple and accurate method to quantify four key antibiotics in dried distillers grains with solubles (DDGS) using high-performance liquid chromatography with charged aerosol detection.

Application Note (AN) 1055: Determination of Virginiamycin, Erythromycin, and Penicillin in Dried Distillers Grains with Solubles demonstrates the ability of a specialized protein and peptide column to efficiently separate and resolve the target antibiotics within 15 min, followed by column cleanup and equilibration for a total analysis time of 25 min.

The U.S. Food and Drug Administration has raised concern over food-producing animals consuming DDGS with antibiotic residues, which potentially may lead to increased antibiotic resistance in humans and animals.

Therefore, to meet possible future regulatory requirements, a screening method is needed to determine residual antibiotics in DDGS.

The multistep sample preparation process and chromatography detailed in AN 1055 provide a quantification method that addresses the challenge of determining the four major antibiotics, with a wide range of physical and chemical properties, used in DDGS production.

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