RTS Life Science and Takeda San Diego Inc Discuss Innovative Automated System for Processing Protein Crystallography
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The groundbreaking HTSB Factory streamlines Takeda San Diego’s protein crystallography operation. Takeda San Diego Inc is Japan-based Takeda Pharmaceutical Company Ltd’s global centre for excellence in structure-based drug discovery.
The innovative HTSB Factory utilizes an industrial robot to provide plate-handling services for multiple concurrent and independent liquid handling processes in a single platform, significantly reducing the capital investment by sharing the system resources common to each process. The system performs three processes: liquid handling for bulk pre-mixed (course screen) crystallization solutions, preparation of custom (fine screen) crystallization solutions and set up of sitting drop vapour diffusion protein crystallization solutions.
The high quality and reliability of the system means it is very economical, achieving high throughput and consistent results with minimal user input. In addition, the novel HTSB Factory allows for the production of commercial screens directly into crystal plates, removing the need for intermediate deep well plates. Supported by a brand new software program developed by RTS Life Science engineers, the HTSB Factory provides an elegant solution to a previously laborious business process.
After a competitive tendering process, Takeda San Diego Inc selected RTS Life Science due to the company’s experience and proven track record in delivering automated sample storage solutions. John Palan, Director of Engineering at Takeda San Diego Inc comments, “The state-of-the-art technologies in the HTSB Factory will clearly continue to enhance Takeda’s R&D pipeline. The system has achieved a high level of performance in the areas of quality, throughput and especially reliability. The most significant overall impact of the system has been to enable Takeda San Diego to continue to meet important structural biology and drug discovery goals as part of the Takeda R&D pipeline.”
This landmark project demonstrates RTS Life Science’s ability to deliver made to order, high quality, automated solutions to the pharmaceutical industry. For further information on how RTS Life Science can assist your company with custom automation solutions, please call +44 (0)161 7772000 or alternatively, please e-mail lifescience.info@rts-group.com.
