Fast LC/MS Sample Preparation Microplate
Porvair Sciences reports how its P3 microplate can be used to accelerate removal of interfering proteins from serum, plasma or even whole blood samples prior to analysis by Liquid Chromatography / Mass Spectrometry (LC/MS). Traditionally scientists have used the CRASH method, in which the protein is denatured with acetonitrile and the flocculant filtered out to clean their samples prior to LC/MS analysis. Benefiting from a novel dual frit hydrophobic filter matrix - the P3 plate overcomes all the traditional ‘wetting out’ and leakage of sample before the application of vacuum problems traditionally associated with the CRASH technique of protein clean-up. Beneficially the P3 microplate also enables 96 samples to be filtered simultaneously – further accelerating your LC/MS protocols.