Covering the complete range from microflow to semi-microflow, Shimadzu’s Nexera Mikros microflow LC-MS/MS system allows operators to realize high sensitivity, yet with the reliability and ruggedness of HPLC.
The system is elegant in design and easy to use. Its UF-Link allows operators to correctly and easily connect any microflow column. The UF-Link ensures a zero-dead volume connection every time. The innovative LC-Mikros pump provides a wide range of flows from micro (0.1 μL/min) to semi-micro (500 μL/min) in both isocratic and gradient elution modes.
The SIL-30AC autosampler provides excellent accuracy, reproducibility, and ultra-low carry-over. It also offers a trap-and-elute function for higher sample volumes and stronger sample matrices. The newly developed programmable loop cut-off mechanism minimizes system volume and gradient delay. The sample loop is taken off-line after injection, minimizing microflow analysis run times.
System configuration options include a direct injection system for sample volume-limited analyses for rapid and highly sensitive micro LCMS analysis without sample loss. A trap and elute system is available for analyses with larger injection volumes or when some degree of sample cleanup is desirable. A make-up flow system includes the addition of a post-column make-up flow pump, allowing mobile phase modifiers to be added to ensure the highest ionization efficiency in the MS source.