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ZenoTOF 7600+ System, Featuring ZT Scan DIA – Taking Biology Beyond ID Numbers
Credit: SCIEX
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The SCIEX ZenoTOF 7600+ system takes quantitative accuracy to the next level. This high-resolution mass spectrometry solution combines powerful MS/MS sensitivity, fragmentation-centric technology and innovative developments in data-independent acquisition (DIA) approaches.
The ZenoTOF 7600+ system offers the selectivity of the scanning quadrupole dimension, high sensitivity MS/MS enabled by Zeno trap pulsing, and fast time-of-flight acquisition rates to improve the detection of quantifiable protein groups by over 125% at sub-nanogram levels when using ZT Scan DIA relative to conventional discrete-window DIA. This innovative method offers precise quantitation of entire proteomes with exceptional speed and sensitivity, overcoming previous limitations.
The SCIEX ZenoTOF 7600+ system takes quantitative accuracy to the next level. This high-resolution mass spectrometry solution combines powerful MS/MS sensitivity, fragmentation-centric technology and innovative developments in data-independent acquisition (DIA) approaches.
The ZenoTOF 7600+ system offers the selectivity of the scanning quadrupole dimension, high sensitivity MS/MS enabled by Zeno trap pulsing, and fast time-of-flight acquisition rates to improve the detection of quantifiable protein groups by over 125% at sub-nanogram levels when using ZT Scan DIA relative to conventional discrete-window DIA. This innovative method offers precise quantitation of entire proteomes with exceptional speed and sensitivity, overcoming previous limitations.
Scan speed, ZT Scan DIA MS/MSUp to 750 Da / second Q1 scan rate with a total MS/MS rate of up to 640 Hz
MS/MS duty cycle When activated the Zeno trap allows ≥90% duty cycle for TOF MS/MS acquisition
Fragmentation modesCollision induced dissociation (CID) and electron activated dissociation (EAD)
Scan modes supported, standardFull scan TOF MS, Full scan TOF MS/MS, MRMHR, Zeno SWATH DIA, IDA (DDA), ZT Scan DIA
Scan modes supported by EADFull scan TOF MS/MS, MRMHR, SWATH DIA, IDA (DDA)
Standard softwareSCIEX OS software version 3.4 or higher
About SCIEX
SCIEX helps to improve the world we live in by enabling scientists and laboratory analysts to find answers to the complex analytical challenges they face. The company's global leadership and world-class service and support in the capillary electrophoresis and liquid chromatography-mass spectrometry industry have made it a trusted partner to thousands of the scientists and lab analysts worldwide who are focused on basic research, drug discovery and development, food and environmental testing, forensics and clinical research.
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