Cancer Diagnostics – Multimedia

Only a small amount of cell-free DNA (cfDNA) can be found in circulation, therefore efficient and highly sensitive technologies such as next-generation sequencing (NGS) are typically being used to detect this biomarker.

Analyzing nucleic acids provides insights into a variety of biological processes. However, the quality of your isolated DNA or RNA has a direct impact on the success of your genomic techniques and applications.

Ambient ionization mass spectrometry techniques that enable direct, gentle, and rapid analysis of samples offer exciting opportunities to provide clinicians with rich molecular data to enhance decision-making. Here, an overview of several ongoing clinical projects in the Eberlin laboratory related to the development of a handheld MS-based device, the MasSpec Pen technology, for improving patient care will be discussed. In particular, I will describe results centered around our efforts in employing the MasSpec Pen for intraoperative tissue analysis and cancer detection, identification of infectious microorganisms, and detection of drugs of abuse.

Speaking at The Landscape of Cancer Research 2021, Prof. Emanuel Petricoin from The George Mason University, presented his talk on pharmacoproteomics.

Download this eBook to explore how these new technologies have enabled some of the most recent discoveries in areas such as molecular mechanisms of cancer, cancer biomarkers as well as vaccines and therapeutics to tackle cancer.

When it comes to cancer, diagnosis often relies on tissue biopsy in conjunction with medical imaging. In addition to sometimes being inconclusive, tissue biopsies are associated with risks, high costs and inconvenience for patients, making them ill-suited for screening or tracking disease progression.

At various points throughout the NGS workflow, QC steps are recommended to avoid time and resource wasting, and to help prevent suboptimal sequencing data.

Download this infographic to learn about the importance of liquid biopsies and their use in cancer diagnosis and monitoring.

In this infographic, we delve into the field of cancer genetics, highlight key milestones and explore how genomic approaches are transforming diagnosis and treatment of the disease in the clinic.

Understanding the integrity and quantity of your nucleic acid samples is critical for next-generation sequencing (NGS) and biobanking workflows.