Spatial Biology – News and Features

At this year’s HUPO annual meeting, the 24th version of the Human Protein Atlas has launched. We interviewed the HPA's program director, Professor Mathias Uhlén, to learn about its new features.

Alzheimer’s disease (AD) progresses in two phases, highlighting early inflammatory changes and the loss of specific inhibitory neurons. Researchers created a cellular timeline, offering potential new targets for therapy.

Researchers have made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis. Using innovative spatial proteomics the team identified the inflammatory JAK/STAT pathway as the main driver of disease.

Technology Networks caught up with Dr. Anne Carpenter at ELRIG Drug Discovery 2024 to learn more about the Cell Painting assay and its impact on the pharmaceutical industry.

A study reveals a detailed atlas of prenatal human skin, uncovering how hair follicles form and the role of immune cells in scarless healing. This research could enhance regenerative medicine approaches.

Researchers developed a method to enhance mesenchymal stromal cells (MSCs) for cartilage tissue regeneration by adding ascorbic acid during cell expansion. This study also highlights micro magnetic resonance relaxometry (µMRR) as a novel tool.

Researchers developed CRISPRmap, an optical pooled screening approach that links the optical properties of single cells to targeted genetic perturbations. This technique enables high-throughput studies of gene function in complex tissues.

Researchers have discovered that combining immunotherapy and chemotherapy can overcome treatment resistance in a subset of lung cancer patients.

Researchers have used cells from cord blood to recreate a functioning human immune system in mice.

Scientists developed NeoDisc, a computational pipeline that combines molecular and genetic analyses with artificial intelligence to identify effective neoantigens for personalized cancer vaccines.