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The Immune System – News and Features

A macrophage.
News

Lipid-Associated Macrophages Drive Liver Repair Post-Injury

Research from VIB-UGent identifies lipid-associated macrophages and LAM-like Kupffer cells as critical for liver repair. The study reveals TREM2's role in clearing damaged cells and promoting recovery.
A doctor examining a child.
News

AI-Powered Blood Test Shows Promise for Diagnosing Long Covid in Children

A collaborative study identifies unique blood plasma biomarkers in pediatric Long Covid patients using AI, achieving a 93% diagnostic accuracy. The test could transform care by enabling definitive diagnosis and targeted treatment.
Image of vaccination needle destroying COVID-19 virus
News

New Vaccine Approach May Aid Future Coronavirus Pandemics

A new experimental vaccine developed by researchers could offer protection against emerging variants of SARS-CoV-2, as well as related coronaviruses, known as sarbecoviruses, that could spill over from animals to humans.
Cancer cells.
News

Combination Immunotherapy Investigated for Melanoma and Breast Cancer

Researchers at MedUni Vienna have developed a combination therapy using systemic interferon-I and topical imiquimod. Effective against local tumors and distant metastases, the therapy improves sensitivity to checkpoint inhibitors.
Mitochrondria.
News

Targeting Mitochondria Function May Help Treat Inflammatory Diseases

Researchers revealed mitochondria's role in immune regulation through IL-10 production, controlled by mitochondrial complex III and ROS signaling pathways. Enhancing mitochondrial function could treat inflammatory diseases like lupus.
Bowls of different salads on a picnic rug.
News

Non-Industrialized Diet, With No Dairy or Wheat, Reduces Risk of Chronic Disease

A diet inspired by non-industrialized societies can significantly reduce the risk of a number of chronic diseases by modulating the gut microbiome.
A person holding a drug delivery "pen"
Article

New Year's Resolution To Lose Weight? Avoid Counterfeit Weight Loss Drugs

High demand and supply shortages of weight loss drugs have presented opportunities for counterfeit drugs to enter the market. So, what are the dangers of counterfeits? And what can consumers look out for?
Illustration of the concept of weight loss using drugs.
Article

Balancing Weight Loss and Muscle Health in the Age of Incretin-Mimetic Drugs

Incretin-mimetic drugs contribute to dramatic weight loss, but this does not solely mean fat loss. In this article, we explore the impact of incretin-mimetic drugs on muscle health and what can be done to limit these severe side effects.
A coil of DNA breaks.
News

DNA Destabilizing Proteins Implicated in Huntington’s Disease Progression

APOBEC enzymes, which normally help fight viral infections by mutating viral DNA, cause repeat expansions and are unusually active in the brains of Huntington’s patients.
Microscope image of gut villi and crypts, with different cell types labelled in different colors.
News

Gut Immune Cells Undergo Surprising Relocation To Fight Infections

Pathogen-fighting immune cells go through a surprising transformation and relocation as they fight infections in the gut.
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