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The Immune System – News and Features

A cartoon of a person's gut, teeming with multicolor bacteria.
News

Largest Collection of Digital Microbes Could Transform Microbiome Research

The world’s largest collection of digital microbes - nearly a quarter million computer models - could help revolutionize our understanding of the human microbiome and its impact on health.
A SARS-CoV-2 virion, with surface proteins shown in red and orange.
News

Researchers Explore the Cellular “Arms Race” for Iron During COVID-19 Infection

New research explores the cellular fight for iron during COVID-19 infection, unraveling the body's defense mechanisms and the viruses means of attack.
Bacteria in the gut.
News

Cystic Fibrosis Disrupts Early Gut Development in Infants

New findings outline the differences in the gut microbiome of infants with cystic fibrosis, compared to healthy infants, and how these changes may affect health.
A strand of DNA coils across the image.
News

Gene-to-Gene Interaction Increases Alopecia Risk

In a new study, researchers have found that changes in two parts of the genome work together to influence alopecia risk.
Microscopic 3D-rendered image of biological cells.
News

How Cancer Exploits the Immune System To Spread Faster

Researchers reveal how MAGE-4 and PTEN loss drive cancer growth, suppress immunity and point to new therapeutic strategies to fight tumors.
A man taking vitamin D.
News

Vitamin E Succinate Helps Control Tumor Growth and Enhance Immunotherapy

Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing tumor growth by promoting FTO degradation. This enhances T-cell cytotoxicity and improves response to immunotherapy.
An ash tray containing cigarette butts.
News

Childhood Secondhand Smoke Exposure Alters DNA

A study from ISGlobal found that second-hand smoke exposure in childhood causes epigenetic changes in 11 DNA regions, potentially affecting disease risk in adulthood. These changes highlight the need for stronger public health measures.
Colorized transmission electron micrograph of mpox virus particles found within an infected cell.
News

Researchers Discover How Mpox Develops Tecovirimat Resistance

Researchers at the Institut Pasteur have uncovered how mpox virus mutations make it resistant to tecovirimat, the primary antiviral treatment. The study reveals that mutations in the F13 enzyme prevent the drug from blocking virus spread.
A pill capsule split open, with the chemical structure of a drug inside.
News

Innovative DNA Hydrogels for Sustained Drug Release

A hydrogel made from DNA holds promise for sustained drug release.
Cancer cells dividing
News

Cancer Cells Trick the Immune System by Altering Mitochondria

Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key mechanism of immune evasion and resistance to immunotherapy.
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