The Immune System – News and Features

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Largest Collection of Digital Microbes Could Transform Microbiome Research
The world’s largest collection of digital microbes - nearly a quarter million computer models - could help revolutionize our understanding of the human microbiome and its impact on health.

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Researchers Explore the Cellular “Arms Race” for Iron During COVID-19 Infection
New research explores the cellular fight for iron during COVID-19 infection, unraveling the body's defense mechanisms and the viruses means of attack.

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Cystic Fibrosis Disrupts Early Gut Development in Infants
New findings outline the differences in the gut microbiome of infants with cystic fibrosis, compared to healthy infants, and how these changes may affect health.

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Gene-to-Gene Interaction Increases Alopecia Risk
In a new study, researchers have found that changes in two parts of the genome work together to influence alopecia risk.

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How Cancer Exploits the Immune System To Spread Faster
Researchers reveal how MAGE-4 and PTEN loss drive cancer growth, suppress immunity and point to new therapeutic strategies to fight tumors.

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Vitamin E Succinate Helps Control Tumor Growth and Enhance Immunotherapy
Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing tumor growth by promoting FTO degradation. This enhances T-cell cytotoxicity and improves response to immunotherapy.

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Childhood Secondhand Smoke Exposure Alters DNA
A study from ISGlobal found that second-hand smoke exposure in childhood causes epigenetic changes in 11 DNA regions, potentially affecting disease risk in adulthood. These changes highlight the need for stronger public health measures.

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Researchers Discover How Mpox Develops Tecovirimat Resistance
Researchers at the Institut Pasteur have uncovered how mpox virus mutations make it resistant to tecovirimat, the primary antiviral treatment. The study reveals that mutations in the F13 enzyme prevent the drug from blocking virus spread.

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Innovative DNA Hydrogels for Sustained Drug Release
A hydrogel made from DNA holds promise for sustained drug release.

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Cancer Cells Trick the Immune System by Altering Mitochondria
Researchers have identified the transfer of mitochondria with mutated DNA from cancer cells to immune cells as a key mechanism of immune evasion and resistance to immunotherapy.
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