Continuous Live Cell Analysis at Sygnature Discovery
In July 2015, Sygnature and Essen BioScience Ltd., a world leader in the field of cell-based in vitro assays and instrumentation, announced that they had established a strategic alliance to incorporate Essen’s unique phenotypic assay, live-cell imaging and ion channel technologies into Sygnature’s integrated drug discovery projects. This alliance has been very productive and has also resulted in the addition of the IncuCyte® ZOOM System by Sygnature into its in-house capabilities. IncuCyte® ZOOM offers plate-based continuous cell imaging within a controlled tissue-culture environment, allowing real time quantitative live-cell, non-invasive analysis. Assaying cellular systems using live-cell imaging affords an array of advantages when compared to classical single end-point functional cellular assay read-outs; these include, label-free analysis, no cell disruption during analysis, multiplexing and kinetic data generation. The adoption of the IncuCyte® ZOOM System has enhanced Sygnature’s research expertise across a broad range of therapeutic areas including oncology, immunology, inflammation and neuroscience.
