Mitigate Interference and Contamination in PFAS Analysis

As per- and polyfluoroalkyl compounds become more prominent, the US Environmental Protection Agency (EPA) are developing more stringent regulations for PFAS monitoring.

In this Teach Me in 10, we hear from field application scientist Marc Elie on the challenges of PFAS analysis in matrices including drinking water and wastewater and how to mitigate interference and contamination on LC-MS/MS instrumentation.

After watching, you’ll understand the differences between analysis for US EPA Methods 537.1, 533 and 1633 as well as the additional difficulties of PFAS analysis in non-potable water.

Further Reading

• Analysis of PFAS in Drinking Water with EPA Method 537.1 Using QSight UHPLC/MS/MS | PerkinElmer
• Improved Throughput for the Analysis of Perfluoroalkyl and Polyfluoroalkyl Substances in Drinking Water by EPA Method 533 | PerkinElmer