Across structural biology research, understanding oligomeric state is essential for determining molecular function and advancing drug discovery.
Phenylketonuria (PKU) is a metabolic disorder caused by a dysfunction in the hepatic enzyme phenylalanine hydroxylase (PAH).
In this webinar, Dr. Kushol Gupta explores how mass photometry was used alongside cryo-EM to study PAH activation.
Watch this webinar to discover:
- The role of mass photometry in interpreting functional mechanisms
- How mass photometry complements other biophysical tools
- How these biophysical measurements enabled insight into PAH activation
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