Latest On-Demand Webinars
Genomic tools for Psilocybe cubensis propagation
Kevin McKernan, CSO at Medicinal Genomics will be joining us to discuss genetic variation in the Psilocybe cubensis synthesis pathway and the design of qPCR assays for simultaneous quantification of E. coli and Salmonella species contamination concurrent with Psilocybe cubensis species identification.
Exploiting the timsTOF and MALDI-2 Platforms to Assess Pharmacodynamics and Pharmacokinetics in Preclinical Models
An integrated evaluation of the pharmacodynamic and pharmacokinetic properties of a drug is essential for successful translation to the clinic. However, cost-effective methods to measure these parameters at the systems level in pre-clinical models are lacking. Here, we introduce a timsTOF and MALDI-2 workflow to evaluate therapeutic activity. The platform combines ion mobility, mass spectrometry-based imaging, absolute drug quantitation across different biological matrices, in vivo isotope tracing, and global metabolome analysis in the adult zebrafish.
Effective Nuclei Isolation From Tissue for Single-Nucleus Sequencing
In this webinar, we present a standardized workflow solution, including easy and automated nuclei extraction and isolation for reproducible single-nucleus sequencing analysis.
Discovering Reprogrammed Molecular Pathways in Cancer Metastasis With MALDI Imaging
This presentation will highlight our recent progress in the discovery of N-glycans and phospholipids that significantly contribute to aberrant cancer metabolic pathways in primary tumors and metastases. We have also developed novel MALDI imaging approaches of drugs and drug metabolites that exploit key metabolic differences in tumors.
Reduce Cost of Matrix-Rich HPLC Separations
How To Increase the Cost Effectiveness for HPLC Separations of Challenging and Matrix-Rich Samples
The Analytical Landscape of Cannabis Testing Session 4: Residual Solvents & Terpenes by GC-MS
In the first part of this webinar, Kirk will talk about headspace sampling and GC-MS measurement of residual solvents using the JEOL JMS-Q1500GC quadrupole GC-MS system, and how the technique can meet California’s minimum reporting limits.
Assessment of Biotherapeutics Quality Attributes Leveraging a Novel Fragmentation Technique
The novel fragmentation technique, electron activated dissociation (EAD) of the ZenoTOF 7600 system (SCIEX), was employed for peptide mapping of a multispecific monoclonal antibody (mAb) as well as IgG1 and IgG4 mAb samples. A specific focus was put on assessing challenging PTMs, such as glycosylations, amino acid isomers and the localization of a sulfation on a singly charged peptide.
How To Design, Select and Implement Application Software To Ensure Data Integrity in GXP Regulated Laboratories
This presentation will cover how to use application software to ensure data integrity. Our speaker, data integrity expert Bob McDowall, will explain how process mapping, audit trails, role selection and access privileges can all play a part.
Developing Mass Spectrometry for Deep and Quantitative Single-Cell Proteomics
Dr. Nemes will share developments from his lab that enabled the in situ and in vivo measurement of metabolites and proteins in single cells in live tissues and organisms, while Dr. Orsburn will explain how leaps in mass spectrometry can facilitate unprecedented sequence coverage of protein at the single-cell level.
Identification of Protein Aggregation Through UV-Visible Spectroscopy
Watch this webinar to learn about how to rapidly recognize the presence of protein aggregates using UV-VIS, the absorption of a protein aggregate can be obtained using an integrating sphere and much more.