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New Oligonucleotide Characterization Workflows With LC-MS/MS

New Oligonucleotide Characterization Workflows With LC-MS/MS content piece image

Mass spectrometry has been growing as the analytical technique of choice to analyze and quantitate oligonucleotide drugs from discovery to QC. Characterization of production related impurities or degradation products is of key importance during the approval process of such biopharmaceutical products. LC-MS/MS provides essentials insights in the identity, amount and sequence of the drug and its impurities.

In this webinar you will:

• Gain a deeper understanding of how to measure oligonucleotide in a robust environment with high isotopic fidelity mass spectrometry

• Discover how OligoQuest™ simplifies the characterization and quantification of oligonucleotide and oligonucleotide degradation products

• Learn about tools to simplify the annotation of oligonucleotide MS2 data

Dr. Stuart Pengelley
Dr. Stuart Pengelley
Application Development Scientist Bruker
Dr. Detlev Suckau
Dr. Detlev Suckau
Global Biopharmaceutical Solutions R&D Manager Bruker