Tech Spotlight: High-Throughput Screening 2026

High-throughput screening has transformed vaccine and antibody discovery by enabling researchers to evaluate large numbers of targets, responses and potential candidates at scale. However, increasing throughput alone does not guarantee meaningful results. Effective screening requires a balance between speed, assay quality, reproducibility and biological relevance to ensure that generated data can support confident scientific decisions. This webinar will explore the development of reliable high-throughput screening workflows, from assay design and miniaturization through to data analysis, validation and candidate prioritization. Attendees will learn how to establish fit-for-purpose assays and controls, manage biological and technical variability, and identify challenges such as batch effects and false-positive hits. The presentation will also examine how functional immunological assays, screening cascades, orthogonal validation and data-driven approaches can help researchers progress from broad discovery screens towards biologically relevant candidates for further investigation. Key learning objectives: • Understand the key considerations when developing reliable HTS workflows. • Learn how to balance throughput, assay quality and biological relevance. • Explore approaches for managing variability and improving reproducibility. • Understand how screening and validation strategies can support candidate prioritization. • Discover how immunological assays and data analysis can strengthen vaccine and antibody discovery.