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Fully Automated Sensitive Determination of Immunosuppressant Drugs in Whole Blood, using High Quality Internal Standardization

Measurement of immunosuppressant drugs is essential during organ transplantation. Under-dosing can lead to organ rejection, while over-dosing can cause serious toxicity.

LC-MS/MS has become the traditional method due to its specificity, precision and sensitivity. However current LC-MS/MS platforms demand personnel with expertise and, for whole blood samples, tedious sample preparation.

Download this whitepaper to learn:
- How a fully automated procedure can increase sample throughput
- The benefits of using 13C labelled internal standards