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The 3230 genes you can’t lose
Industry Insight

The 3230 genes you can’t lose

The 3230 genes you can’t lose
Industry Insight

The 3230 genes you can’t lose

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A new study has shown that 15% of the twenty thousand genes in our bodies play a key role that they can kill us before we born even small mutations occur. These findings, however, can help researchers the gene that causes diseases.

“Any information that can help us better understand the genetic basis of diseases is priceless.” said Kári Stephánsson, one decoding geneticist from Reykjavik.

Published in a sample library, this new study has not yet been published to the peer-reviewed journals. The researchers compared the protein-coding exons of sixty thousand people, the number of which is more than an order of magnitude of the previous experiment. Among these genes, the researchers found 1,000 mutated gene locus, but the mutation positions varied from different people.

The team calculated the probability of each random genetic mutations and compared it with the actual mutation rate. They found that the probability of mutations for 3203 of the genes is far less than what has expected and even no pathogenic mutations were occurred.

These data suggested that when one of those genes changed, the embryo will usually die or lose fertility. Then the variation would disappear. “Genes without mutation are what we need or we say are the ones that play an important biological function.” said Ping Xu, a molecular microbiologist from Richmond Virginia Commonwealth University.

Ping and other found that bacteria and rats also have this similar essential gene. Many of the key human gene are associated with important cellular operations, such as the cell’s protein-building factories. “These genes can be used to detect toxic and side effects in drug development.” Ping said.

The success of this team lies in the collecting of so much data. “They have done a good job. Through the investigation of this huge group, they get more information.” Commented Joshua Akey, population geneticist from the University of Washington in Seattle.

Written by Caroline from Creative BioMart.