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Supercritical Fluid Chromatography Guide

Supercritical Fluid Chromatography Guide content piece image

Supercritical fluid chromatography (SFC) is a separation method that uses supercritical carbon dioxide as the mobile phase. Due to recent advancements in SFC instruments and column technologies, SFC is now beginning to be utilized for regular lab use and measurements. CO2 cylinders used for SFC are filled with supercritical carbon dioxide generated by industrial plants, meaning that no new carbon dioxide is generated for operating SFC. Therefore, switching the separation method from HPLC to SFC reduces the quantity of greenhouse gasses emitted, achieving one of the sustainable development goals proposed by the United Nations.

Download this guide to learn more about:

  • The basics of SFC
  • SFC set-up and workflows
  • Method development and settings 
  • A variety of SFC applications