Bacteria Be Gone!
News Jan 19, 2015
Just as the invention of nonstick pans was a boon for chefs, a new type of nanoscale surface that bacteria can’t stick to holds promise for applications in the food processing, medical and even shipping industries.
The technology, developed collaboratively by researchers from Cornell University and Rensselaer Polytechnic Institute, uses an electrochemical process called anodization to create nanoscale pores that change the electrical charge and surface energy of a metal surface, which in turn exerts a repulsive force on bacterial cells and prevents attachment and biofilm formation. These pores can be as small as 15 nanometers; a sheet of paper is about 100,000 nanometers thick.
When the anodization process was applied to aluminum, it created a nanoporous surface called alumina, which proved effective in preventing surrogates of two well-known pathogens, Escherichia coli O157:H7 and Listeria monocytogenes, from attaching, according to a study recently published in the journal Biofouling. The study also investigates how the size of the nanopores changes the repulsive forces on bacteria.
“It’s probably one of the lowest-cost possibilities to manufacture a nanostructure on a metallic surface,” said Carmen Moraru, associate professor of food science and the paper’s senior author. Guoping Feng, a research associate in Moraru’s lab, is the paper’s first author.
Finding low-cost solutions to limiting bacterial attachments is key, especially in biomedical and food processing applications. “The food industry makes products with low profit margins,” said Moraru. “Unless a technology is affordable it doesn’t stand the chance of being practically applied.”
Anodized metals could be used to prevent buildups of biofilms – slick communities of bacteria that adhere to surfaces and are tricky to remove – in biomedical clean rooms and in equipment parts that are hard to reach or clean, Moraru said.
Anodized metal could also have marine applications, such as keeping ship hulls free of algae.
The collaborating group from Rensselaer Polytechnic Institute is led by Diana Borca-Tasciuc, associate professor of mechanical, aerospace and nuclear engineering.
Nanoparticles show great promise as diagnostic tools and drug delivery agents. But until now, most nanoparticles had to be injected into the bloodstream because they weren’t absorbed well orally. Now, researchers have modified nanoparticles to improve their uptake in the gastrointestinal tract.